Mr Fabio Castiglione

MD, PhD

Consultant Urologist and Andrologist

Dr Fabio Castiglione is a London-based Consultant Urologist and Andrologist specializing in erectile dysfunction (ED), Peyronie’s disease, male fertility and complex sexual-function surgery. He holds NHS consultant posts at King’s College Hospital NHS Foundation Trust and Guy’s and St Thomas’ NHS Foundation Trust, and is also the Director and Founder of Holistic Andrology Clinic.

Professional Profile

Dr Castiglione is widely described as a pioneer in regenerative medicine for male sexual disease, with a research track record spanning stem-cell science, translational andrology and innovative therapies for Peyronie’s disease and erectile dysfunction. He completed a PhD in stem cells and erectile dysfunction at KU Leuven, and his work is cited as among the earliest clinical studies exploring stem cells and PRP in Peyronie’s disease.

His international standing is reflected in major honours from the leading scientific societies in sexual medicine, including the ISSM Rising Star Award from the International Society for Sexual Medicine and the ESSM Award of Excellence (2022) from the European Society for Sexual Medicine.

Dr Castiglione has authored 150+ peer-reviewed publications across andrology, sexual medicine, male infertility, reconstructive urology and regenerative medicine, contributing to consensus work and multicentre research that underpins modern practice in men’s health.

Areas of Clinical Expertise

Dr Castiglione provides end-to-end care for men seeking a clear, expert pathway—from diagnosis and optimisation of modifiable contributors, through advanced therapies where appropriate, to definitive surgery when indicated. His clinic focus includes

Erectile Dysfunction (ED)

Medical optimisation and advanced treatment planning, including shockwave therapy pathways for selected patients and modern ED diagnostics when clinically needed

Penile rehabilitation and ED after radical prostatectomy

Expertise in sexual rehabilitation after prostate cancer surgery, supported by recognised pathway-improvement work focused on post-treatment sexual dysfunction

Peyronie’s disease

Comprehensive management from early-phase symptoms through complex deformity, with a strong research pedigree in regenerative approaches

Male fertility

Assessment and treatment of male-factor infertility, andrology pathways and partner-centred fertility care

Major andrological surgery

Including complex genital/sexual-function surgery and penile implant surgery for men with severe ED when other treatments have failed

Procedures & Treatments

Kidney & Bladder Stones

Robotic intrarenal stone surgery (RIRS)
Ureteroscopy (for stones and cancer diagnosis)
Percutaneous Nephrolithotomy (PCNL)
Extra corporal shockwave lithotripsy (ESWL)
Bladder stone removal (Laser Endoscopic litholapaxy / Percutaneous cystolithotomy)

Prostate & Bladder Care

Enlargement (BPH): HoLEP, Rezum, Aquablation, Urolift, Green Light Laser, TURP, and iTIND.
Cancer Diagnosis: PSA testing, MRI Fusion Transperineal Prostate Biopsy, and TURBT (Bladder).
Incontinence: Bladder Botox, Autologous Fascial Sling, PTNS, and Urethral Bulking.

Advanced Urological Reconstruction

Ureteric Stricture: Balloon dilatation and specialized stenting (Resonance, Memokath, Hilzo, Allium).
Urethral Stricture: Optical urethrectomy and dilatation.
Scrotal & Penile Surgery: Circumcision, Vasectomy (and Reversal), Varicocele repair, and Orchidectomy.